Orchid

Study looking to understand why people with different chest conditions develop a cough and how their cough compares to people without a chest condition.

• Cough is a protective reflex that is used to clear the airways of irritating material or phlegm and is one of the most common issues for which people seek medical advice. Cough is a common feature of a range of different chest and respiratory conditions and can be associated with poor quality of life.
• The results of this study will help researchers understand the mechanisms of coughing and may be used to help improve treatments in the future.
• This international study is being carried out by a team of researchers at the North West Lung Centre, part of Manchester University NHS Foundation Trust.

• Diagnosed with asthma, COPD or IPF (idiopathic pulmonary fibrosis)
• Never smoked (or quit at least six months ago)
• Not currently taking ACE inhibitors (eg ramipril, enalapril)

• Wythenshawe Hospital (M23 9LT, part of Manchester University NHS Foundation Trust)

• Attending four clinic visits, each lasting approximately 1 hour, over a 6-week period.
• Clinic visits will include a range of tests (eg blood samples, blood pressure checks, breathing tests) as well as questions about lifestyle and medical history.

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