This study is looking for healthy volunteers to help develop a new approach to diagnosing iNPH (idiopathic normal pressure hydrocephalus), a brain disorder that can lead to difficulty walking, problems with thinking and reasoning, and loss of bladder control.
There is currently no research providing in-depth measurements of someone’s gait (pattern of walking), making it difficult to distinguish iNPH from other conditions that also affect gait.
It is being carried out by a team of researchers based at Salford Royal Hospital (part of the Northern Care Alliance), Manchester Metropolitan University and Gothenburg University, and is funded by the Hydrocephalus Association.
This study is investigating whether a home-based exercise programme can help people recently diagnosed with type 1 diabetes (T1D) slow down the progression of the disease.
It is part of the Exercise for Type 1 Diabetes (EXTOD) programme, which aims to provide evidence-based support for people living with diabetes to be able to undertake safe and effective exercise.
The study is being led by a team of researchers at the University of Birmingham.
Testing the effectiveness of an online intervention for parents with bipolar disorder.
Parents with bipolar disorder (BD) can find that the ups and downs of mood they experience can make parenting challenging. Many parents with BD want parenting support but worry they might lose access to their children if they disclose this to their clinicians.
The integrated bipolar parenting intervention (IBPI) in an accessible, flexible, and confidential online resource that can support parents to help their children flourish.
The IBPI has been developed by a team of researchers, clinicians, and parents with BD at Lancaster University in collaboration with Lancashire & South Cumbria NHS Foundation Trust.
The GLAD (Genetic Links to Anxiety and Depression) study is looking to understand why some people experience anxiety and depression by exploring the influence of genetic and environmental risk factors on these disorders.
Anxiety and depression are the most common mental health disorders worldwide. Findings from this study will be used to help find effective treatments and improve the lives of people experiencing these disorders.
It is being led by the National Institute for Health and Care Research (NIHR) Mental Health BioResource and researchers at King’s College London, in collaboration with researchers at the universities of Ulster, Edinburgh and Cardiff.
Outdoor and indoor pollutants have been linked to a variety of adverse health effects including increasing the risk of cardiac disease and lung diseases. It is thought that air pollution may also cause problems with memory and the brain’s ability to process information.
This study will investigate the effect of common air pollutants on brain function in healthy participants who have family members with brain disorders such as dementia.
It is being carried out by a team based at The University of Manchester and Manchester University NHS Foundation Trust and is funded by the Natural Environment Research Council.
This study is looking to understand and reduce fatigue-related symptoms experienced by people after infection with COVID-19.
Further research will assess the feasibility of a self-help intervention to help reduce symptoms of fatigue in long COVID.
This study is being led by a team of researchers based at The University of Manchester and the Salford Care Organisation (part of Northern Care Alliance NHS Foundation Trust). It is funded by FORME (Charity No: 1045005).
Investigating the effects of a time restricted eating programme on blood sugar control for people who have been told they are at risk of developing type 2 diabetes.
Results from this study will be used to inform future research to help prevent people from developing type 2 diabetes.
It is being carried out by a team of researchers at Manchester Metropolitan University in collaboration with Newcastle University and the Northern Care Alliance NHS Foundation Trust.
Many people with allergy and asthma live with pet cats. However, it is not known for sure whether the presence of cats makes allergy or asthma symptoms worse. This project will assess new tests to measure this.
It is being carried out by a team of researchers at The University of Manchester and will form part of a doctoral degree.
The Genetic Association study in individuals of Diverse Ancestral backgrounds with Multiple Sclerosis (ADAMS)
This study is looking to understand how changes in the genetic code can cause multiple sclerosis in people from different ancestral and ethnic backgrounds.
This study is led by a team of researchers based at Queen Mary University of London. It is funded by the Medical Research Council, the MS Society and Barts Charity.
This study will investigate the genetic causes of Parkinson’s Disease and other movement disorders to help develop new and improved treatments.
It is being carried out by a team of researchers based at University College London.
This study will test two different low-calorie diets aimed at helping people with type 1 diabetes lose weight and improve their blood glucose control.
The study will look at daily and intermittent low-calorie diets that have already been proven to be successful to help people with type 2 diabetes lose weight and improve blood glucose control.
The findings of this initial study will be used to inform further research.
It is being carried out by a diabetes specialist team at Wythenshawe Hospital, part of Manchester University NHS Foundation Trust.