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MoNoPly study

MoNoPly (Models of Nociceptive Plasticity in Chronic Pain), understanding how the brain processes pain and how it learns and adapts to sensory experiences over time.

Many people with musculoskeletal disorders experience severe pain which is often poorly managed with medications or surgical treatments. This study is looking to better understand how the brain processes pain and how it learns and adapts over time. This phenomenon is referred to as ‘nociceptive learning’.  Findings from this study will be used to improve diagnosis and treatment options for people experiencing chronic pain.

This study is being carried out by a team of researchers from the University of Liverpool.


  • Aged 18+

Have either

  • Experience pain from inflammatory arthritis (eg gout, lupus, rheumatoid arthritis, psoriatic arthritis)


  • No experience of long-term pain (healthy volunteers)


  • Aintree University Hospital (L9 7AL, Liverpool)


  • Attending two clinic appointments. You will be asked to complete several questionnaires and undergo some tasks that involve recording your brain activity with EEG.
  • Participants will receive reimbursement for their time, plus travel and parking expenses.

Recruiting until

  • 31 March 2023

Want to take part or learn more?