This study will investigate whether an omega-3 fatty acid supplement can improve skin changes after menopause.
It is being carried out at Salford Royal Hospital (part of the Northern Care Alliance NHS Foundation Trust) by a team of researchers from The University of Manchester. It is funded by the Biotechnology and Biological Sciences Research Council (BBSRC).
This study will determine if ondansetron, a drug already used in the NHS, can be used as a treatment for visual hallucinations in people with Parkinson’s Disease or Lewy Body Dementia.
Visual hallucinations can be a common and distressing feature of Parkinson’s Disease and can have a significant impact on quality of life.
The Trial of Ondansetron as a Parkinson’s HAllucinations Treatment or TOP HAT is being carried out by researchers at the Northern Care Alliance on behalf of a team at UCL (University College London).
This study will measure the effects of pomegranate extract supplements on blood pressure, cholesterol, and inflammation, as well as muscle and brain function.
Findings from this project will be used to inform future research looking at the combination of antioxidants and lifestyle factors (such as physical activity) on healthy ageing.
It is being carried out by a team based at the Manchester Metropolitan University (MMU).
This project is looking to investigate if supplements containing Hericium erinaceus mushroom (also known as lion’s mane) can help improve memory and cognition in young adults.
It is being carried out as part of a student-led Master’s research project at The University of Manchester.
It is quite difficult to use an inhaler properly, and many people who use inhalers for their asthma make mistakes. This can mean that the full dose is not reaching the lungs and that people may not be treated as well as they can be or may experience more side effects from the medicine.
This study is testing a new tool designed to help people take their inhaler effectively. The tool has two parts, a small device that fits onto the inhaler and a companion smartphone app. Participants will be randomly allocated to either use the new tool, or to continue with their usual care,
It is being carried out by a team of researchers at The University of Manchester
MND-SMART (Motor Neurone Disease – systematic multi-arm adaptive randomisation trial) is looking to understand whether certain medications currently used to treat other conditions, could be used to help slow down the progression of motor neurone disease.
It is being carried out by a team based at the Euan Mac Donald Centre for MND Research at the University of Edinburgh.
The CHIEF-PD trial is looking to determine if a certain medication can help prevent falls in people with Parkinson’s Disease.
Falls are a common complication of Parkinson’s and can lead to injuries and reduced confidence when walking. Previous trials have highlighted that drugs called cholinesterase inhibitors, used to treat dementia and memory problems, can help make walking steadier and therefore reduce the number of falls people experience.
This study is being carried out by researchers from the University of Bristol and is funded by Royal United Hospitals Bath NHS Foundation Trust.
This study wants to find out how blood pressure control can be improved and whether people are getting the best out of their current medications.
It is funded by the British Heart Foundation and sponsored by The University of Manchester.
The national PRINCIPLE trial is looking to find low-risk treatments that can be taken at home for people with COVID-19 symptoms.
This study wants to find out whether medications currently prescribed to treat people with diabetes and heart problems could be used to prevent heart problems.
It is being carried out by a team of researchers at the University of Vienna, with the University of Glasgow and NHS Greater Glasgow and Clyde acting on their behalf in the UK.
Investigating whether treating iron deficiency with injections can prevent people with heart failure from being admitted to hospital and improve their overall outcomes.
Further reading
- Kalra, P.R., Cleland, J.G.F., Petrie, M.C., Thomson, E.A., Kalra, P.A., Squire, I.B., Ahmed, F.Z., Al-Mohammad, A., Cowburn, P.J., Foley, P.W.X., Graham, F.J., Japp, A.G., Lane, R.E., Lang, N.N., Ludman, A.J., Macdougall, I.C., Pellicori, P., Ray, R., Robertson, M. and Seed, A. (2022). Intravenous ferric derisomaltose in patients with heart failure and iron deficiency in the UK (IRONMAN): an investigator-initiated, prospective, randomised, open-label, blinded-endpoint trial. The Lancet. doi:10.1016/s0140-6736(22)02083-9.
